Design Considerations, Architecture, and use of the Mini-Sentinel Distributed Data System

Project Title Design Considerations, Architecture, and use of the Mini-Sentinel Distributed Data System
Date
Sunday, February 5, 2012
Location
Description

This article describes the design, implementation, and feasibility of a large, multiorganizational distributed database developed to support the FDA’s Mini-Sentinel pilot in which contributing organizations retain possession of the source data. The paper focuses on development of a common data model and analytic tools that enable rapid querying of the data locally by data partners.

Corresponding Author

J. S. Brown, Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, 401 Park Drive, Suite 401 East, Boston, MA 02215, USA. Email: jeff_brown@harvardpilgrim.org

Authors

Jeffrey S. Brown PhD; Lesley H. Curtis PhD; Mark G. Weiner MD; Denise M. Boudreau RPh, PhD; William O. Cooper MD, MPH; Gregory W. Daniel PhD, MPH; Vinit P. Nair BPharm, MS, RPh; Marsha A. Raebel PharmD; Nicolas U. Beaulieu MA; Robert Rosofsky MA; Tiffany S. Woodworth MPH