Antidepressant Use and Bleeding Events

Project Title Antidepressant Use and Bleeding Events
Date Posted
Friday, May 20, 2016
Project ID
MSY4_MPR17
Status
Complete
Deliverables
Description

Modular program-based one-time assessment of the use of antidepressants (SSRIs, SNRIs, and tricyclics) and risk of bleeding events among members with a pre-existing condition of depression and members with no pre-existing condition requirements. The query was run against the Mini-Sentinel Distributed Database (MSDD) for the time period of January 1, 2009 through December 31, 2011.  Modular programs are adaptable standardized programs. Results were generated using Modular Program 3, version 1.0; click here for more information.  Queries were distributed in February 2012. This report includes data from 18 Data Partners.
 
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Medical Product
antidepressant
selective serotonin reuptake inhibitor (SSRI)
serotonin-norepinephrine reuptake inhibitor (SNRI)
tricyclic
Health Outcome
bleeding event
gastrointestinal hemorrhage
intracerebral hemorrhage (ICH)
Population / Cohort
All individuals
Time Period
January 1, 2009 to December 31, 2011
Assessment Type
Exploratory Analyses
Study Type
Modular Program
Data Sources
Mini-Sentinel Distributed Database (MSDD)
FDA Center
CDER