Isotretinoin and Long-term Antibiotic Use and Multiple Sclerosis

Project Title Isotretinoin and Long-term Antibiotic Use and Multiple Sclerosis
Date Posted
Thursday, June 30, 2016
Status
Complete
Deliverables
Description

Report 1 is a modular program-based one-time assessment of isotretinoin and long-term antibiotics, including doxycycline, minocycline, and erythromycin, and subsequent multiple sclerosis (MS) diagnoses. Report 2 is a modular program-based one-time assessment of multiple sclerosis diagnoses as defined in three different ways. The queries were run against the Mini-Sentinel Distributed Database (MSDD) for the time period of January 1, 2000 to May 31, 2013.  Modular programs are adaptable standardized programs. Results were generated using Modular Program 3; click here for more information.  Queries were distributed in July 2014. This report includes data from 17 Data Partners.
 
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Medical Product
abacavir
doxycycline
erythromycin
isotretinoin
lamivudine
long-term antibiotic
minocycline
zidovudine
Health Outcome
multiple sclerosis
Time Period
January 1, 2000 - May 31, 2013
Assessment Type
Exploratory Analyses
Study Type
Modular Program
Data Sources
Mini-Sentinel Distributed Database (MSDD)
FDA Center
CDER